REVIEW
Pan-cancer analysis shapes the understanding of cancer biology and medicine
Xiaoping Cen, Yuanyuan Lan, Jiansheng Zou, Ruilin Chen, Can Hu, Yahan Tong, Chen Zhang, Jingyue Chen, Yuanmei Wang, Run Zhou, Weiwei He, Tianyu Lu, Fred Dubee, Dragomirka Jovic, Wei Dong, Qingqing Gao, Man Ma, Youyong Lu, Yu Xue, Xiangdong Cheng, Yixue Li, Huanming Yang
Cancer Communications 2025 45: [Abstract ] [ PDF Full-text ] [ HTML Full-text ] [ PubMed] Epub: 3/22/2025 doi:10.1002/cac2.70008
ORIGINAL ARTICLE
Immunosuppressive JAG2+ tumor-associated neutrophils hamper PD-1 blockade response in ovarian cancer by mediating the differentiation of effector regulatory T cells
Chenyang Wang, Moran Yang, Yujing Zhong, Kankan Cao, Xueling Wang, Chen Zhang, Yiying Wang, Mengdi He, Jiaqi Lu, Guodong Zhang, Yan Huang, Haiou Liu
Cancer Communications 2025 45: [ PDF Full-text ] [ HTML Full-text ] [ PubMed] Epub: 3/22/2025 doi:10.1002/cac2.70021
LETTER TO THE JOURNAL
Deletion of epithelial HKDC1 decelerates cellular proliferation and impairs mitochondrial function of tumorous epithelial cells thereby protecting from intestinal carcinogenesis
Lea J?rke, Saskia Weber-Stiehl, Kensuke Shima, Karlis Arturs Moors, Jerome Genth, Fenja Amrei Schuran, Lena Best, Markus Tschurtschenthaler, Burkhardt Flemer, Silke Lüschen, Christoph R?cken, Andreas Tholey, Christoph Kaleta, Jan Rupp, Philip Rosenstiel, Felix Sommer
Cancer Communications 2025 45: [ PDF Full-text ] [ HTML Full-text ] [ PubMed] Epub: 3/20/2025 doi:10.1002/cac2.70022
LETTER TO THE JOURNAL
Targeted intracellular delivery of molecular cargo to hypoxic human breast cancer stem cells
Ashley V. Makela, Anthony Tundo, Huiping Liu, Doug Schneider, Terry Hermiston, Pavlo Khodakivskyi, Elena Goun, Christopher H. Contag
Cancer Communications 2025 45: [Abstract ] [ PDF Full-text ] [ HTML Full-text ] [ PubMed] Epub: 3/20/2025 doi:10.1002/cac2.70018
LETTER TO THE JOURNAL
Whole-genome CRISPR-Cas9 knockout screens identify SHOC2 as a genetic dependency in NRAS-mutant melanoma
Andrea Y. Gu, Tet Woo Lee, Aziza Khan, Xuenan Zhang, Francis W. Hunter, Dean C. Singleton, Stephen M. F. Jamieson
Cancer Communications 2025 45: [Abstract ] [ PDF Full-text ] [ HTML Full-text ] [ PubMed] Epub: 3/17/2025 doi:10.1002/cac2.70013
LETTER TO THE JOURNAL
Comprehensive DSRCT multi-omics analyses unveil CACNA2D2 as a diagnostic hallmark and super-enhancer-driven EWSR1::WT1 signature gene
Florian Henning Geyer, Alina Ritter, Seneca Kinn-Gurzo, Tobias Faehling, Jing Li, Armin Jarosch, Carine Ngo, Endrit Vinca, Karim Aljakouch, Azhar Orynbek, Shunya Ohmura, Thomas Kirchner, Roland Imle, Laura Romero-Pérez, Juan Díaz-Martín, Stefanie Bertram, Enrique de álava, Clémence Henon, Sophie Postel-Vilnay, Ana Banito, Martin Sill, Yvonne Versleijen-Jonkers, Benjamin Friedrich Berthold Mayer, Martin Ebinger, Monika Sparber-Sauer, Sabine Stegmaier, Daniel Baumhoer, Wolfgang Hartmann, Jeroen Krijgsveld, David Horst, Olivier Delattre, Patrick Joseph Grohar, Thomas Georg Phillip Grünewald, Florencia Cidre-Aranaz
Cancer Communications 2025 45: [Abstract ] [ PDF Full-text ] [ HTML Full-text ] [ PubMed] Epub: 3/15/2025 doi:10.1002/cac2.70015
ORIGINAL ARTICLE
Blocking ITGA5 potentiates the efficacy of anti-PD-1 therapy on glioblastoma by remodeling tumor-associated macrophages
Rongrong Zhao, Ziwen Pan, Jiawei Qiu, Boyan Li, Yanhua Qi, Zijie Gao, Wei Qiu, Weijie Tang, Xiaofan Guo, Lin Deng, Gang Li, Hao Xue
Cancer Communications 2025 45: [ PDF Full-text ] [ HTML Full-text ] [ PubMed] Epub: 3/14/2025 doi:10.1002/cac2.70016
NEWS AND VIEWS
Reflections and insights into the evolution of restrictive eligibility criteria for cancer clinical trials in China and beyond
Huiyao Huang, Huilei Miao, Jinling Tang, Ning Li
Cancer Communications 2025 45: [ PDF Full-text ] [ HTML Full-text ] [ PubMed] Epub: 3/12/2025 doi:10.1002/cac2.70007
LETTER TO THE JOURNAL
Rare germline ATM variants predispose to secondary cancer in chronic lymphocytic leukaemia patients
Anna Petrackova, Jirina Manakova, Romana Nesnadna, Zuzana Kubova, Tomas Papajik, Eva Kriegova
Cancer Communications 2025 45: [Abstract ] [ PDF Full-text ] [ HTML Full-text ] [ PubMed] Epub: 3/12/2025 doi:10.1002/cac2.70010
LETTER TO THE JOURNAL
Dlk1 is a novel adrenocortical stem/progenitor cell marker that predicts malignancy in adrenocortical carcinoma
Katia Mariniello, James F. H. Pittaway, Barbara Altieri, Kleiton Silva Borges, Irene Hadjidemetriou, Claudio Ribeiro, Gerard Ruiz-Babot, David S. Tourigny, Jiang A. Lim, Julie Foster, Julie Cleaver, Jane Sosabowski, Nafis Rahman, Milena Doroszko, Constanze Hantel, Sandra Sigala, Andrea Abate, Mariangela Tamburello, Katja Kiseljak-Vassiliades, Margaret Wierman, Charlotte Hall, Laila Parvanta, Tarek E. Abdel-Aziz, Teng-Teng Chung, Aimee Di Marco, Fausto Palazzo, Celso E. Gomez-Sanchez, David R. Taylor, Oliver Rayner, Cristina L. Ronchi, Carles Gaston-Massuet, Silviu Sbiera, William M. Drake, Emanuel Rognoni, Matthias Kroiss, David T. Breault, Martin Fassnacht, Leonardo Guasti
Cancer Communications 2025 45: [Abstract ] [ PDF Full-text ] [ HTML Full-text ] [ PubMed] Epub: 3/4/2025 doi:10.1002/cac2.70012
